Professor David de Kretser, A.C. GOVERNOR OF VICTORIA


Date of Birth:27 April 1939
Professor David de Kretser, Governor of Victoria
 
Citizenship:Australian
 
Awards:2006Companion of the Order of Australia
2000Officer of the Order of Australia
2003Centenary Medal
 
Qualifications:1962Bachelor of Medicine, Bachelor of Surgery
University of Melbourne
1969Doctor of Medicine
Monash University
1976Fellow, Royal Australian College of Physicians
1996Fellow, Australian Academy of Science
2001Fellow, Australian Academy of Technological Sciences and Engineering
 
Postgraduate Training and Experience:
1963 - 1964Resident Medical Officer, Prince Henry’s Hospital
1965Demonstrator, Dept. of Anatomy, Monash University
1966 - 1968Lecturer, Dept. of Anatomy, Monash University
1968Senior Lecturer, Dept. of Anatomy, Monash University
1969 - 1971Senior Fellow in Endocrinology, Dept. of Medicine, University of Washington, Seattle, USA.
1969 - 1971USPHS International Postdoctoral Fellow
1971 - 1975Senior Lecturer, Depts. Medicine & Anatomy, Monash University
1971 - 1985Assistant Endocrinologist, Prince Henry’s Hospital
1973 - 1974Physician, Prince Henry’s Hospital
1974 - 1978Senior Research Fellow, Medical Research Centre
Prince Henry's Hospital
1976 -Consultant, Reproductive Medicine Clinic, Prince Henry’s Institute of Medical Research
1976 - 1978Reader in Anatomy, Monash University
1977 - 1978Associate Director, Medical Research Centre, Prince Henry’s Hospital
1978 - 1991Professor & Chairman, Dept. of Anatomy, Monash University
1991 - Professor, Dept. of Anatomy, Monash University
1989 - 1991Director, Centre for Reproductive Biology
1985 -Specialist, Infertility Clinic, Monash Medical Centre
1991 - 2005Director, Institute of Reproduction and Development, Monash University
 
Past Appointments:
2001Associate Dean, Biotechnology Development, Faculty of Medicine, Monash University
1999Director, Australian Centre for Excellence in Male Reproductive Health (Andrology Australia)
1991Professor, Monash Institute of Medical Research , (formerly known as Monash Institute of Reproduction and Development), Monash University
2003Sir John Monash Distinguished Professor
 
Board Director:
2001 - 2004The Walter Eliza Hall Institute of Medical Research – Member and Director
2002 – 2003CRC for Chronic Inflammatory Diseases
2001 - Marshall Edwards Inc. and Marshall Edwards Pty Ltd
2001Biocomm International Pty Ltd and Biocomm Services Pty Ltd – Member and Director
2002 -Monash IVF Pty Ltd
2003 -Australian Phenomics Facility
2003 -Camberwell Grammar School Council – Member and Director
2005 -Advanced Plastic Surgery Education Foundation
 
National & International Committees:
1974 -1979Member of WHO Task Force on “Methods of Regulation of Fertilizing ability of Sperm”.
1978 -1985Member, Steering Committee of WHO Task Force on “Diagnosis & Treatment of Infertility:
1980 -1982Member, Advisory Board, Programme on Human Reproduction. World Health Organisation
1974 -1979Member, Executive Council for “Committee Internacional de Andrologia”
1982 -1983President, Anatomical Society of Australia & N.Z.
1985 -1990President, International Society of Andrology
1978 -1981President, Australian Society of Reproductive Biology
1981 -1999Member, NH & MRC Regional Grant Interviewing Committee
1985 -1989NH & MRC Special Purposes Committee
1993 -2001Member, Scientific Advisory board Committee, Co-Operative Research Centres for the Biological Control of Vertebrate Pest Populations
1992 -1996Member, Australian Prostate Health Council
1992 -1999Member, Scientific Advisory Board, Australia Stroke & Neuroscience Institute
1997 -FIGO Expert Advisory Panel on Andrology
1998 -Fellow: Intl. Academy of Human Reproduction
1998 - 2001Member Intl. Advisory Panel National University of Singapore
1999 - 2002Board Member, Bertarelli Foundation
1999 - 2000Australian Research Centre in Sex, Health & Society (ARCSHS) Scientific Advisory Committee
1999 -Infertility Treatment Authority of Victoria – Panel of Advisers, Clinical and Scientific Panel
1999 – 2001Medical Board, Bonnie Babes Foundation
1999 -Director, Australian Centre of Excellence in Male Reproductive Health, Andrology Australia
2001- 2004Chair, Australian Academy of Science Victorian Governmental Liaison Group
2001- 2003Member, Board of Directors, CRC for Chronic Inflammatory Diseases
2001-Chair, BioMelbourne Network, Committee for Melbourne
2001- 2003Member, Scientific Advisory Committee, Tony Hitchin Foundation
2001 -2004Chair, Platform Technologies Steering Group, Department of Industry, Innovation and Regional Development, Victorian Government
2002 -Advisory Committee Member, Bertarelli Foundation
2004 -Member, Diabetes and Endocrinology Evaluation Board of the Faculty of 1000 Medicine and Faculty Member of the Reproductive Endocrinology Section.
 
Editorial Boards:
1973 - 1977Member, Andrologia
1974 - 1977Associate Editor, Andrologia
1976 - 1982Member, Board of Molecular & Cellular Endocrinology
1978 - 1991Associate Editor, Int. Journal of Andrology
1980 - 1991Member, Advisory Board, Australian Journal of Biological Sciences
1981 - 1989Member, Clinical Reproduction & Fertility
1989 - 1992Member, Reproduction, Fertility & Development
1993 - 1995Member, Oxford Reviews of Reproductive Biology
1994 - 1998Member, Journal of Andrology
1995 – 2001Member, International Advisory Panel for Reviews of Reproduction
1997 -Member, Gynaecological Endocrinology
1997 - 2000Scientific Editor, Journal of Endocrinology
1999 - 2000Section Editor, Cell & Tissue Research
2001 -Member of Editorial Board, Journal of Endcrinology
2001 -Member Editorial Board, Molecular Human Reproduction
2002 -Review Editorial Board, Reproduction
2004 -Member Editorial Board, The Journal of Clinical Endocrinology & Metabolism
 
Membership of Societies:
American Society for Andrology
Anatomical Society of Australia & New Zealand
Australian Academy of Sciences
Australian Society for Medical Research
Society for Reproductive Biology Inc, Life Member
Comite Internacional de Andrologia
Endocrine Society of America
Endocrine Society of Australia
Fertility Society of Australia
International Academy of Human Reproduction
International Society for Andrology
Royal Australasian College of Physicians
Society for Study of Reproduction
 
Honours and Awards:
Undergraduate:1st Class honours, Physics, Chemistry, Surgery
2nd Class honours, Physiology, Biochemistry, Pathology
3rd Class honours, Microbiology, Medicine, Obstetrics & Gynaecology
Burroughs Wellcome Prize in Physiology
John Adey Prize in Psychiatry
Beaney Scholarship in Surgery
Prince Henry’s Hospital Staff Award
 
Postgraduate:Wyeth Award, Annual Meeting Pacific Coast Fertility Society, 1970
Organon Prize, Australian & New Zealand Endocrine Societies, 1977
Serono Lecturer, American Society for Andrology, 1985
2003 Distinguished Andrologist Award, American Society for Andrology
HS Jacobs President’s Lecturer, British Fertility Society 2004
2004 Robert H Williams Distinguished Leadership Award, (US) The Endocrine Society
2005 ASMR Edwards’ Orator
 
Committee Responsibilities at Monash University:
1978 -Professors Committee, Faculty of Medicine
1978 -Member, Board of Faculty of Medicine
1978 -Member, Academic Board
1985 - 1986Associate Dean (Campus)
1989 - 1991Associate Dean (Campus)
1982 -Chairman, University Animal Services Committee
1982 -Ex-Officio Member, University Animal Ethics Committee
1987 - 1989Steering Committee of Academic Board
1987 - 1988University Research Committee
1990 - 1990Acting Dean, Faculty of Medicine
1991 - 1992Associate Dean (Research), Faculty of Medicine
1998 - 1998Acting Dean, Faculty of Medicine
1998 -Member of Executive, Faculty of Medicine
2001 -Executive Chair, Monash Institutes of Health Steering Committee
2001 -Member, Faculty of Medicine Research Committee
2003 -Member, Faculty of Medicine Board Steering Committee
 
Conferences / Symposiums / Invited speaker at the following:
1971Int. Conf. on gonadotrophins, Cornell Medical School, New York
1972Symposium on Male Infertility, IV Int. Cong. Endocrinology
1973Serono Symposium on Male Reproduction, Milan.
1974Int. Planned Parenthood Federation Workshop “Agends affecting Fertility in Men”. India.
VIIIth World cong. on Fertility & Sterility, Argentina.
1976The Royal Society Sponsored Symposium on “Contraceptives of the Future”, London
3rd National Institutes of Child Health & Human Develop. Conference, Pittsburgh.
1st International Congress of Andrology, Barcelona
Vth International Congress of Endocrinology, Hamburg.
World Health Organisation Sponsored Symposium on “Advances in Fertility Regulation, Moscow.
Confernece on “Reproduction & Evolution”, Canberra
Postgraduate Committee in Veterinary Science, Semen Refresher Course, Sydney.
1977Serono Symposium on “Recent Advances in Andrology”, L’Aquila.
1978VIth Asian & Oceania Congress of Endocrinology, Singapore.
1979VIth National Institutes of Child Health & Human Development Meeting “The Testis”, Houston, U.S.A.
ANZAAS Meeting, New Zealand
World Health Organisation, Workshop in Infertility, Nairobi.
1980Symposium on New Methods of Fertility Regulation in Beijing.
1981World Health Organisation Workshop in Male Fertility, Singapore.
2nd International Congress of Andrology, Israel.
1982International Congress on Therapy in Andrology, Italy.
International Congress on Advances in Molecular Basis of Reproduction, Italy.
Indonesia Society for Andrology, Indonesia.
Pacific Coast Fertility Society, Arizona, USA.
Australian Society for Reproductive Biology.
Australian Society for Medical Research Symposium on Cell to Cell Communication, Canberra.
1983World Congress Fertility & Sterility, Ireland.
National Institutes of Health Workshop on Testis, Washington, USA.
World Health Organisation, Workshop on Male Fertility, China.
1984World Health Organisation, Workshop on Andrology, China.
19853rd International Congress of Andrology, Boston, USA.
5th Congress on Human Reproduction, Greece.
WHO Symposium on Infertility, Yerevan.
1986AFFPA Biological Science Symposium, NSW.
X Renunion de la Asociacion Cahno Americana de Investigaciones en Reproduction, Humana, Santiago.
U.S. Endocrine Society, California, USA.
Karolinska/Serono Symposium “Fertility Regulation Today & Tomorrow”, Sweden.
XIIth World Congress of Fertility and Sterility, Singapore.
1987Serono Symposium on “Inhibin”, Japan.
WHO Special Programme, Development & Research Training in Human Reproduction, China.
Symposium on “New Gonadal Peptides”, US Endocrine Society, USA.
IVth Pan American Congress of Andrology & Serono Symposium on “Human
Reproduction”, Brazil.
European Society for Paediatric Endocrinology, Denmark.
Vth World Congress of Human Reproduction, Japan.
1988Australian Societies for Experimental Biology on “Fertility Regulation in Man,
Native Mammals and Domestic Livestock”, Canberra.
Biological Sciences Meeting, Threadbo.
Vth European Workshop on “The Molecular & Cellular Endocrinology of the Testis” England.
British Endocrine Societies Symposium on “Inhibin”. England.
Golden Jubilee Meeting, Australia.
International Congress of Endocrinology, Japan. Plenary Lecture.
Australian Endocrine Society Meeting, Sydney.
Inaugural Scientific Meeting, “New Frontiers in Medicine”, Melbourne.
Study for Society for Reproduction, Seattle, USA.
Joint WHO/NICH Symposium “Potentials of Molecular Biology in Fertility Regulation”, USA.
Ringberg Symposium on “New Approaches to the Pathophysiology of Male Infertility”. West Germany.
International Symposium on Gamete Physiology, U.S.A.
1989IVth International Congress of Andrology, Italy
71st Annual Meeting of the Endocrine Society, U.S.A.
Symposium on GnRH and Gonadal Peptides. France
Combined Meeting of FSA and ASRB, Australia
Japanese Urological Association, Japan.
Serono Symposium, California, U.S.A.
1990Hormonal Communicating Events in the Testis, Italy.
Jubilee Symposium “Anatomy in Finland”. Turku, Finland.
VIth European Workshop on the Testis, Finland.
42nd Annual Meeting of the Scandanavian Society for Electron Microscopy, Finland.
1991Anatomical Society of Australia and N.Z. Plenary Lecture. New Zealand.
73rd U.S. Endocrine Society Meeting, Washington.
Int. Symposium on Molecular & Cellular Biology of Reproduction, Italy
Int. Symposium on Sperm Preservation & Encapsulation, Australia.
19923rd World Congress on Gynaecological Endocrinology, Italy.
Int. Symposium “New Perspectives in Andrology & Assisted Fertility, Brazil.
Satellite Symposium on Gonadotrophins, GnRH, GnRH Analogs & Gonad Peptides, Paris, France.
Ninth International Congress of Endocrinology, Nice.
Task Force on the Prevention & Management of Infertility (WHO), Malaysia.
First Asian & Oceanic Congress of Andrology, China.
Symposium on Advanced Assisted Reproductive Techniques for Infertile Men, Adelaide
1993Biological Sciences Meeting of the Family Planning Federation of Australia, Queensland
Vth International Congress of Andrology, Japan.
Int. Symposium on “Inhibin & Inhibin-Related Proteins”, Italy.
VIIIth World Congress in In Vitro Fertilization & Alternated Assisted Reproduction, Japan. Plenary Lecture.
Invited to deliver the Dr. S.T. Huang-Chan Memorial Lecture at the University of Hong Kong.
1994Boden Conference, Thredbo.
6th International Congress of Andrology, Belgium.
Int. Symposium on Intracytoplasmic Sperm Injection, Queensland.
VIIth International Meeting on Spermatology, Cairns.
Reproductive Medicine, “Beyond 2000” Carl Wood Festchrift, Melbourne.
33rd National Scientific Conference, ASMR, Melbourne.
1995Boden Conference “Marsupial Gametes & Embryos”, Thredbo.
The Second International Androgen Workshop, California, USA.
Fertility Society of Australia, Melbourne.
1996XV Annual Meeting of the Fertility Society of Australia, New Zealand
Int. Conference on Intracytoplasmic Sperm Injection: Basic & Clinical Aspects, Greece.
Int. Symposium on Inhibin, Activin and Follistatin, Tokushima, Japan.
1997Symposium on “Hormones & Men’s Health”, Melbourne
4th Copenhagen Workshop on Carcinoma in situ. Denmark
VIth International Congress of Andrology, Austria
U.S. Endocrine Society,
Paracrine Mechanisms and Female Reproduction, Spain
Indonesian Andrology Society
Intl. Symposium on Genetics of Human Fertility, France
‘Medical Focus Australia’ Bangkok
Founders Lecture, Australian Society for Reproductive Biology
15th Anniversary of the Concept Fertility Centre, Perth
The Fertility Society of Australia XVI Annual Scientific Meeting
1998Treatment of Infertility’ Florida USA
Boden Conference on The Epididymis: Cellular and Molecular Aspects
Australasian Society of Impotence Medicine
ASMR 37th National Scientific Conference
189th Meeting of the Society for Endocrinology, London
1999American Society of Andrology – ASA Postgraduate Course
11th World Congress on In Vitro Fertilization & Human Reproductive Genetics
ESHRE’99 – France
International Conference on Gonadal Failure – Italy
2000Endocrine Basis of Reproductive Function – Tampa Florida
Fertility Society of Australia, Canberra
European Testis Workshop, France
IIIrd Asian and Oceanic Congress of Andrology – Chiba, Japan
Serono Conference – Inhibin/Activin/Follistatin Meeting – Melbourne
11th International Endocrine Conference – Sydney
Inaugural Conference in Gender Health for GP’s – Noosa, Qld
WHO Symposium – Reproductive Health Research in the Asia Pacific – Canberra
2001Biotecha-ONETM – Colonial Stadium, Melbourne
German Australian Business Conference, Berlin
2002Serono Symposia International Conference, Brussels
Andrology Special Interest Group Pre-Congress Course, Vienna
Annual Meeting, European Society of Human Reproduction and Embryology, Vienna
Urological Society of Australian, Western Australian Branch Conference, Bunbury
2nd Bertarelli Global Conference – Prague, Czech Republic
2003American Society of Andrology, Testis Workshop, Phoenix, USA
New World of Medicine Conference, Prato, Italy
5th World Symposium - Inhibins, Activins and Follistatins, Siena, Italy
5th National Men's Health Conference, Palm Cove
41st Annual Meeting of the Australasian Association of Clinical Biochemists, Gold Coast
48th Annual Meeting of the Japanese Society of Fertility and Sterility, Tokyo Japan
2004Ferring Conference on Reproductive Medicine, Marco Island, Florida
Howard Jacobs Lecturer, British Fertility Society
Symposium Speaker, Endocrine Society, USA
Harvard Reproductive Endocrine Sciences Center Clinical Conference, Boston, Massachusetts, USA
2005University of Giessen, Germany
Copenhagen Workshop on Environment, Reproductive Health and Fertility, Rigshospitalet, Copenhagen, Denmark
30th Annual Conference American Society of Andrology, Co-Chair Symposium II – Androgen Regulation of Reproductive Tissues”, Seattle, USA
8th International Congress of Andrology, “Men’s Health – Nature and Nurture”, Seoul, Korea
Symposium, “Post-Meiotic Approaches to Male Contraception”, Hong Kong
Prostate Cancer Symposium, University of Melbourne, Aug 2005
Australasian Sexual Health Conference, Plenary Speaker “Androgen Deficiency: Diagnosis and Treatment”, Hobart, August 2005
ESA Annual Scientific Meeting, Co-Chair ESA Orals – Reproduction/Pregnancy/ Parturition 2, Perth, September 2005
The Edwards’ Oration, ASMR National Scientific Conference, November 2005, Couran Cove, Qld
2006International Symposium. “Genetics of Male Infertility”, Keynote Speaker – The Genetics of Male Infertility: From Bench to Bedside. Salt Lake City, January, 2006
 

Patents:
US5470826 : Title: “Single chain proteins with FSH suppressing activity isolated from follicular fluid and uses thereof.” De Kretser DM, Burger HG, Hearn MTW, Robertson DM, Wettenhall REH, McLachlan RI, de Vos F. Issued Nov. 28, 1995. Filed Nov. 3, 1993.
‘A method of diagnosing abnormal cell growth’ International Patent Application No PCT/AU98/00385
Modulation of Cell Growth and Methods Relating Thereto’ International Application No: PCT/AU98/00292
‘A Novel Spermatogenesis Factor’ Australian Application No: PQ3051.
‘A Cell Regulation Factor, and Uses Thereof’, Patent No. PCT/AU00/01177, Filed: 22 September 2000
“Follistatin Isoforms” Provisional Patent No 2003905010 (Filing Date 15 Sep 2003)
“Therapeutic Method”, (KL Jones, DM de Kretser and DJ Phillips) Ref No 703587 (Filing Date 6 Oct 2003) Provisional Patent No 2003905461)
Follistatin PCT “Composition and method for the treatment of disease” Provisional Patent No PCT/AU02/00945
“Therapeutic Method” Australian Provisional Patent Application No 2004902056 (Confirmed 16 April 2004) (To be cognated with Australian Provisional Patent No 2003905461)
“Assessment Method” International Patent Application No PCT/AU2004/000350 (International filing date 19 March 2004)
PCT Patent: de Kretser DM., Phillips DJ, Jones KL, O’Hehir R, Patella R, Wilson KM and Sebire KL Reference PCT/Au2004/001359, filed 06/10/04.

Patent Assignment
(Ref IPL Monash Deed of Consent dated 1 Dec 2003)
 
INHIBIN PATENTS
 
Native Inhibin
CountryNumberStatus
Australia636318Granted
Austria0185034Granted
Belgium0185034Granted
CanadaApp. # 482 470application pending
France0185034Granted
Germany0185034Granted
Israel75412Granted
Italy0185034Granted
Japan2521707Granted
Japan2583030 (divisional)Granted
Netherlands0185034Granted
Norway176570Granted
New Zealand212248Granted
South Africa85/4346Granted
Sweden0185034Granted
Switzerland0185034Granted
United Kingdom0185034Granted
United States5,102,807Granted
United States5,364,837Granted
 
Recombinant Inhibin
CountryNumberStatus
Australia610821Granted
Belgium0218717Granted
CanadaApp. # 506791application pending
France0218717Granted
Germany0218717Granted
Japan2652534Granted
New Zealand215829Granted
South Africa86/2848Granted
South Korea77916Granted
Switzerland0218717Granted
TaiwanNI-55814Granted
United Kingdom0218717Granted
United States6,613,891Granted
 
Actions of Hormones
CountryNumberStatus
Australia611041Granted
 
FOLLISTATIN PATENTS
 
CountryNumberStatus
Australia610858Granted
Belgium0 299 050Granted
France0 299 050Granted
Germany0 299 050Granted
Italy0 299 050Granted
Japan2802633Granted
Netherlands0 299 050Granted
Sweden0 299 050Granted
Switzerland0 299 050Granted
United Kingdom0 299 050Granted
United States5,470,826Granted

Students Supervised / Visiting Postdoctoral Fellows:
Ph.D. Students supervised:
Baker HWGAu CLKlein R (jointly)
Lee VWKLaws AOTorney AH (jointly)
Kerr JBWilton LJDrummond A (jointly)
Bremner WJ (USA)Hedger MPHancock AD (jointly)
Rich KAYates CMoran O (jointly)
Hodgson YMO’Leary PCSimorangkir D (jointly)
Risbridger GPJackson AE (jointly)Mallidis C
Jegou B (France)Mendis-Handagama SMLC (Sri Lanka)Le Gac F (France)
Sun YTMcLachlan RI (jointly)Gerdprasert O (Thailand)
Meehan T (jointly)Kim YH (jointly)Lin Shyr-Yeu (Taiwan)
Okuna Y (jointly)Hickox D. (jointly)Duckett R (jointly)
Jones K (jointly)McManamny P (jointly)Cotton L (jointly)
Goldman, D (jointly)Kennedy C (jointly)Swain, L (jointly)
Craythorn, Rebecca
 
Honours, B.Med.Sci Students:
Lording DWHayes T
Hodgson YMWongprasartsuk S
Laws AOPirdas A
Wilton LJGoodman M
Adey CGibbons A
Hedger MPRussell C
Torney AJones K
 
Postdoctoral Fellows and Trainees in Laboratory:
Pepperell RI Fingscheidt U (Germany)Regueyra C (Costa Rica)
Padron RS (Cuba)Yohkaichiya T (Japan)Treetampinich C (Thailand)
Robertson DMQin JX (China)Loveland K (Australia)
Wu F (UK)Tong JS (China)O’Bryan MK (Australia)
Arsyad KM (Indonesia)Huidobro C (Chile)Morrison J (Australia)
Zhang GY (China)Leung A (Hong Kong)Hedger MP (Australia)
Tepe SJ (USA)Hauser R (Israel)Phillips D (Australia)
Ishida H (Japan)Gandolfi T (Italy)Weerasooriya T (Sri Lanka)
Bandaso R (Indonesia)Meinhardt A (Germany)Kumara M (Sri Lanka)
Gonzales GF (Peru)Schlatt S (Germany) Ochsenkuhn R (Germany)
Wang ZX (China)Imade G (Nigeria)Naya, Y (Japan)
Hayashi, T (Japan) Saito, K (Japan)Takazawa, R (Japan)


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